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Cross-references to ChemSpider (8116997), DrugBank (DB12509 / DBSALT002878), and MedChemExpress (HY-18678) are concordant on identity and mass
The copper chelation appears to facilitate cellular uptake through copper transport proteins expressed in keratinocytes and fibroblasts
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ICARUS-LUNG01: a phase 2 study of datopotomab deruxtecan (Dato-DXd) in patients with previously treated advanced non-small cell lung cancer (NSCLC), with sequential tissue biopsies and biomarkers analysis to predict treatment outcome