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NICE guidelines recommend evidence-based weight management through dietary modification (600 kcal/day deficit), 150300 minutes weekly moderate-intensity physical activity, and behavioural change strategies
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In patients with type 2 diabetes, systemic chronic inflammation, caused by hyperglycemia and insulin resistance, participates in the development of vascular complications, and contributes to HF (Tsalamandris et al., 2019)
Additionally, sequential use of the medications, starting with GLP-1 receptor agonists, appears to lead to more significant weight loss
Preventing the progression of CRS impacts overall cardiovascular outcomes in CAR-T cell patients
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