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Exploratory endpoints included achieving 15% and 20% weight loss, and patient-reported outcomes assessed using the SF-36 v2.0 and the Three-Factor Eating Questionnaire (TFEQ-R18 v2)
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It has been shown that SIRT1 expression was reduced in toxin-induced and genetically modified PD models (Ubaid et al
Acknowledgments We thank the study participants, and the investigators and study site staff who conducted the study
There are some evidence suggesting that genetics may play a role
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