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These medications work by activating GLP-1 receptors in the brain and pancreas, reducing appetite, slowing gastric emptying, and improving glycemic control
These rare complications are also primarily due to the drug slowing stomach emptying, Kothari says
But the data gets more interesting when you look at the combination with hormone replacement therapy
That matters because many online comparisons treat these compounds as interchangeable
Of particular note, GLP-1 interacts with its G-protein coupled receptor, GLP-1R, to exert stimulatory action on adenylyl cyclase
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