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84 The overexpression of circHECTD1 leads to increased expression levels of p62, ATG5, and ATG9 via the inhibition of miR-182-5p, which activates AMPK/mTOR signaling and reduces colonic injury and inflammation by promoting autophagy

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adult usage of weight-loss medications has more than doubled from 5.8% in early 2024 to 12.4% in 2Q/3Q 2025

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