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However, there was a substantial shift in craving frequency among smokers.The proportion of participants reporting rarely or never craving nicotine increased from 4.6% (18 participants) before GLP-1 use to 22.6% (88 participants) after GLP-1 use

This stability particularly benefits patients requiring sustained GLP-1 therapy over months or years where coverage disruptions risk therapeutic discontinuation

10.1080/02713683.2021.2021586 55 DongX.ZhangJ.LiW.LiY.JiaL.LiuZ.et al (2024)

Manufacturers are in the process of making new GLP-1s that are easier to produce, store, and administer

It does mean you should factor review inconsistency into your risk assessment when deciding how to allocate your research budget

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