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Yes, variants in the GLP1R gene (e.g., rs6923761) have been associated with differences in weight loss response to GLP-1 medications in clinical studies
In essence, its like a melting or dissolving of fat, achieved by triggering the bodys own chemical mechanisms
But its notable that GLP-1s have become one of the largest blockbuster drugs to ever exist
Perspectives in GLP-1 research: new targets, new receptors
This helps lower blood sugar and signals the body to burn fat, rather than store it
Another trial looked at the risk of specific harms among people with existing addictions when they took the different types of medication
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