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Description

Funding This study was supported by the National Key R&D Program of China (2025YFC2708300), National High Level Hospital Clinical Research Funding (2022-PUMCH-B-083) and the National Key Clinical Specialty Construction Project (U114000)

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Eli Lilly's FY2024 performance was extraordinary: total revenues of USD 45.0 billion, up 32% year-on-year, driven by Mounjaro (approximately USD 11.5 billion full-year, a more than 4 increase from 2023) and Zepbound (approximately USD 4.9 billion for its first full year of obesity indication sales, including the landmark Q4 figure of USD 1.9 billion)

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Mean weight loss was 13.9% on Wegovy versus 2.7% on placebo

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In females specifically, IN delivery suppressed PI3K-AKT-mTOR signaling (FDR = 0.062)

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American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings: Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD)

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Severe cramping, extreme nausea, or dizziness warrants prompt contact

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