Common effects include: Nausea Constipation Vomiting Diarrhea Bloating Reduced appetite Less common but serious risks may include: Gallbladder disease Pancreatitis Severe dehydration Patients with certain thyroid cancer histories may not be appropriate candidates for some GLP-1 medications
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For example, older adults with sarcopenia may be at the highest risk, as a further reduction in lean mass could jeopardize overall health and mobility
There have been anecdotal reports of some patients using these drugs for weight loss and then presenting with repeated episodes of nausea and vomiting secondary to a condition referred to as gastroparesis, Mahyar Etminan, the studys senior author and an epidemiologist and ophthalmology and visual sciences professor at the UBC Faculty of Medicine, said in a statement