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To view or add a comment, sign in For nearly two decades, enzyme replacement therapy (#ERT) for #MPS-I has meant essentially one thing: a weekly, hours-long intravenous infusion that sustains patients but leaves two territories almost untouched the brain and the bone

Miller et al., 2000)

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GST activity was recorded at 340 nm and at 25C, following the conjugation reaction of 1-chloro-2,4-dinitro-benzene (CDNB) to GSH ( 340 = 9.6 mM 1 cm 1 )

Measurement of oxidative stress markers was performed by measuring oxidative stress in vivo with simple and accurate tests, d-ROMs-derived compounds and BAP test