10.1530/JME-12-0166 12 ErdogduO.NathansonD.SjholmA.NystrmT.ZhangQ
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If anything, pressure is only intensifying as Novo and Lilly continue to jockey for dominance, and as new challengers look to tap into this burgeoning market
In addition, GLP-1 increases the activity of protein kinase C (PKC) in islet cells in a dose-dependent manner, promotes pancreatic -cell survival, and inhibits mitochondria-dependent apoptosis by regulating Bcl-2/Bax expression levels (Zhang et al., 2015)
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