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Contraindications : It should not be used in patients with a history of medullary thyroid carcinoma, MEN2, severe gastroparesis, pregnancy, or uncontrolled GI disease

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The reasons cited by the FDA included concerns about immunogenicity, peptide impurity characterization challenges, and the lack of adequate safety data from human clinical trials

Retatrutide is a novel triple receptor agonist targeting GLP-1, GIP, and glucagon receptors under clinical evaluation for obesity and type 2 diabetes

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The individuals involved in the leadership of these connected entities have a documented legal history that directly relates to pharmaceutical manufacturing integrity