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Trial STEP 3 (Wadden et al., JAMA 2021) Design Phase 3 / 68 weeks Population 611 adults with obesity + intensive behavior therapy Key result -16.0% body weight (2.4 mg) vs -5.7% placebo

Oxford Health Biomedical Research Centre

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GLP-1, a natural hormone made in our body after we eat food is released from special cells called L-cells that are present in the intestine

That combination is rare in the peptide space

Nonetheless, consistent weekly dosing remains essential for optimal diabetes management and reducing long-term complications