The ER maintains cellular homeostasis through processes like ER-associated degradation and the unfolded protein response (UPR), which manages protein folding during stress [140, 141]
Starting at a low dose and gradually increasing over weeks helps minimize digestive side effects and gives your body time to adjust
Vitamin B12 deficiency can lead to depression and consistently low mood
It has been reported that urolithin A also increased total GSH, lowered oxidative stress, and improved cardiac function in the myocardium of diabetic rats [174]
Morin hydrate overcomes this resistance by simultaneously inhibiting PARP1 and blocking protective autophagy, thereby synergistically enhancing cisplatins cytotoxicity
Anaemia and metabolic factors : Diabetes-related complications including chronic kidney disease can cause anaemia, manifesting as breathlessness and fatigue