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[5] Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P
Using fatty acids to prolong the duration of the action of peptides and proteins was already a long established technique at Novo Nordisk and elsewhere and had been successfully applied to insulin (insulin detemir) (Knudsen, Lau)
PMID: 28868790
Sulbactam, Durlobactam (Xacduro) was officially approved by the FDA on May 23, 2023, for the treatment of pneumonia caused by certain difficult-to-treat bacteria
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Moreover, presence of sequences with different subcellular localizations in the same phylogenetic group inferred the possibility of gene duplication events in formation of some APX/GPX sequences
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