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Braz J Pharm Sci
GIP receptor activation enhances glucose disposal, whilst GLP-1 receptor activation provides glucose-dependent insulin secretion, creating optimal glycaemic control without excessive glucose production from glucagon receptor modulation
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There's good support for patience here: time to therapeutic effect remains similar at roughly 8 to 12 weeks regardless of escalation speed, so patients don't sacrifice their treatment timeline by following gradual protocols
Search strategy and databases Two researchers independently searched four databasesPubMed, Scopus, Web of Science, and the Cochrane Libraryand retrieved all eligible articles published up to November 8, 2024
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