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It exists in both its reduced state (GSH) as well as an oxidized state (GSSG), and the relative amounts of each determine the redox status of a cell ( Fig

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The activated iodine binds to tyrosine residues on thyroglobulin molecules under the action of TPO to produce monoiodotyrosine (MIT) and diiodotyrosine (DIT), which are subsequently coupled to produce T3 or T4 ( Figure 1 )

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