Ipamorelin | Aib-His-D-2-Nal-D-Phe-Lys-NH | Selective GHS-R1a Agonist | Research Peptide Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH Classification: Synthetic pentapeptide selective growth hormone secretagogue receptor 1a (GHS-R1a) agonist / GHRP Molecular Formula: CHNO Molecular Weight: 711.85 g/mol Key Structural Features: -aminoisobutyric acid (Aib) at position 1

DOI: Published online: May 1, 2025 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea 2 Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Corresponding author: Jae Hyun Bae Department of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea E-mail: [email protected] Copyright 2025 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited
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GLP-1RAs compared to placebo In addition, the pooled results showed that first line use of GLP-1RAs has a significant predisposing effect on diarrhea (OR: 2.18, 95% CI: 1.32, 3.60