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Leptin, implicated in inflammatory, mitogenic, and pro-angiogenic pathways, has been associated with breast cancer development, with studies indicating that inhibiting leptin signaling reduces the growth of breast cancer induced by carcinogens [12]
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While more research is needed in this area, a study looking at GLP1 receptor agonist use and opioid overdose risk in patients with type 2 diabetes and opioid use disorder (OUD) found that semaglutide was associated with reduced opioid overdose risk in patients with comorbid T2D and OUD
