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Kurtzeborn said it took her months to recover, and it was almost two years before she was willing to try a weight-loss drug again

The evidence is modest

In cultured H9c2 cells, GLP-1RAs attenuate the production of mitochondrial and intracellular reactive oxygen species (ROS) induced by methylglyoxal

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The list of FDA-approved indications for this class of medication has grown as of late (and currently includes type 2 diabetes, obesity, cardiovascular event risk reduction, obstructive sleep apnea, chronic kidney disease, and metabolic dysfunction-associated steatotic liver disease), and areas of interest for potential future indications are just as long and farreaching

Many users transition to a longer skin or general wellness protocol after the acute phase resolves