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the PDE-5 inhibitor such as sildenafil the PT-141 dose is administered as an IN spray

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We placed 3xTg mice as well as non-transgenic (NTg) controls on a series of dietary regimens with similar compositions and investigated whether the benefits of CR on AD are mediated by energy restriction, fasting, or a combination of both

A structured maintenance dose after the initial loading phase helps sustain results long term without overuse