Semaglutide GLP-1 (Wegovy, Ozempic) Semaglutide is a GLP-1 receptor agonist that works by mimicking a natural hormone that helps regulate appetite and calorie intake
It is unique because it is encoded in the DNA of your mitochondria, not the DNA found in your cells nucleus
The peptide demonstrates dual-phase mechanisms: acute phase preservation of ischemic tissue through anti-apoptotic signaling via Akt activation, and chronic phase activation of cardiac progenitor cells (c-kit+ populations) that contribute to myocardial repair through both structural replacement and paracrine support, with studies showing 200% increases in progenitor cell mobilization and cardiac homing
Im now on Metformin and Ozempic, down under 22% body fat and down 25kg, 23kg or so of which is fat
Inject subcutaneously, preferably in the morning before training
The 14-day spacing matches the typical 7-to-14-day window controlled microneedling studies use, and it gives the skin barrier full time to recover between sessions