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P.RuizL.FolgueiraC.RadaP.Gomez-SantosB.SolasM.et al (2024)
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Vial size and dose count: A 2 mL vial at 10 mg/mL contains 20 mg total
Contraindications are similar to metformin: avoid with renal failure or severe liver disease
Call 999 if severely unwell with signs of shock or collapse
Enzyme-responsive progelator cyclic peptides for minimally invasive delivery to the heart post-myocardial infarction
Recent evidence from the STEP-HFpEF and STEP-HFpEF-DM trials provides the first robust data supporting the efficacy of GLP-1 RAs, specifically semaglutide, in improving the quality of life in obese patients with HFpEF
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