Available from: [Last accessed on 2025 Jun 27].
Ian Neeland, MD Yeah, and I definitely think thats a real concern
Contact your GP or prescribing clinician if you experience cold intolerance accompanied by other symptoms that might suggest thyroid dysfunction, such as: Extreme fatigue or weakness that interferes with daily activities Unexplained weight gain or cessation of weight loss despite adherence to treatment Significant hair loss or changes in hair texture Persistent constipation unresponsive to usual measures Dry, flaky skin or changes in skin texture Muscle aches, cramps, or weakness Slowed heart rate Depression or significant mood changes Cognitive difficulties, including memory problems or difficulty concentrating These symptoms could indicate hypothyroidism , which requires investigation through thyroid function tests (TSH, free T4)
3.1 Impact on Estrogen Research into semaglutides effects on estrogen levels is still emerging
However, the related mechanism of blood oxygen content and serum ions in a hypoxic environment must be studied further
Upper gastrointestinal endoscopy It is a thin, flexible tube equipped with a camera that is inserted through the mouth to examine the esophagus and stomach from the inside and evaluate the presence of infections or abnormal changes in the upper digestive system