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doi: 10.1007/s10238-022-00888-z 66 RuytinxPProostPVan DammeJStruyfS

Glutathione acts as a buffer, ensuring the cells within the kidneys remain resilient

Lipoic acid may also trigger antioxidant defense, enhance cellular glucose uptake, and modulate the activity of various cell-signaling molecules and transcription factors

This peripheral restriction is fundamentally different from compounds like Semaglutide (a GLP-1 agonist that acts centrally to reduce appetite) or ghrelin-modulating agents that directly influence hunger hormones

Importantly, recent research progress has substantially broadened our understanding of the additional physiological functions of erythrocytes

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