Who Is a Good Candidate, and Who Should Avoid It Because the evidence and safety data are limited, candidacy is decided carefully and conservatively
Only medical experts who are truly qualified to perform anti-aging treatments should administer them
This delivers the clinically studied dose without the need to guess or measure anything
From a pharmacological safety perspective, the adverse effect profile of retatrutide based on Phase 1 and Phase 2 clinical trial data (including the NEJM 2023 Phase 2 trial) includes: Gastrointestinal effects: Nausea, vomiting, diarrhoea, and constipation (the most commonly reported side effects in trial participants) Injection site reactions: Redness, swelling, or discomfort at the injection site Cardiovascular effects: Increases in heart rate have been observed in trial participants [21] [22] Hypoglycaemia: Particularly relevant in individuals with diabetes or those taking insulin, sulfonylureas, or other glucose-lowering agents Potential thyroid effects: GLP-1 receptor agonists have been associated with thyroid C-cell changes in rodent studies
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Lower baseline levels were linked to a faster rate of new chronic disease accumulation over the following years