Similarly, a post-hoc analysis of SURPASS-1, enrolling 478 patients with T2D, found that all doses of tirzepatide as monotherapy increased insulin sensitivity compared to placebo, as suggested by the decreases in HOMA2-IR by 923% (vs +14.7% with placebo) and fasting insulin levels by 212% (vs +15%) and the increase in adiponectin by 1623% (vs 0.2%) and IGFBP-2 by 3870% (vs +4.1%) at 40 weeks [76]
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People with darker skin often have more melanin
This treatment is not suitable for individuals who are pregnant/breastfeeding, or those with pacemakers, heart conditions, active thrombosis, diabetes, epilepsy, auto-immune conditions, or active skin infections (psoriasis/eczema) in the treatment area
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What GLP-1 receptor agonists actually are GLP-1 receptor agonists are a completely different class of medication