is glp-1 harmful Clinical Recommendations to Manage Gastrointestinal Adverse Events in Patients Treated with Receptor Agonists: A Multidisciplinary Expert Consensus GLP-1 Agonist: The Good, the

The first study to demonstrate the effect of GLP-1RAs in reducing cardiovascular events was LEADER, in which 9340 patients with type 2 diabetes at high cardiovascular risk were randomized to liraglutide 1.8 mg per day or placebo [16]

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Research has shown that estrogen deficiency (as in menopause) leads to decreased GLP-1 secretion, and estrogen replacement reverses this effect [3]

Another study evaluating cardiovascular outcomes of GLP-1RAs was the HARMONY study

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