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Consequently, the regulation of the expression of the membrane transporter SLC7A11, NADPH depletion because of glucose starvation, and subsequent disruption of the balance of thiol/disulfide bonds may serve as a common link between disulfidptosis and ferroptosis (Figure 2), potentially involving intersecting molecular pathways
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GSH also plays an important role in energy metabolism
In humans, calbindin-D 28K is encoded by the CALB1 gene which is expressed in the kidney tubule and is responsible for participating in renal Ca 2+ reabsorption
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