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GLP-1 Clinical Trials Show Promising Reduction in Body Weight The most cited GLP-1 study is the STEP 1 trial , which evaluated semaglutide, the active ingredient in Wegovy, in non-diabetic adults with obesity

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Dehydration while taking Ozempic is possible because certain early side effects, including vomiting and diarrhea, can cause a loss of fluids

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Zhang H, Sturchler E, Zhu J, et al

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Synergistic effects: The energizing effects of bupropion can be complemented by the increased fullness and metabolic benefits of GLP-1 receptor agonists

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Many patients start with it to see how they respond to GLP-1 alone

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