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Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy
Long-term safety data for subcutaneous injection is limited
Two 2013 systematic reviews of interventions concluded that the modest benefit of propionyl-L-carnitine on walking performance was equivalent or superior to that obtained with drugs approved for claudication in the US (e.g., pentoxyphylline, cilostazol) yet inferior to improvements seen with supervised exercise interventions (69, 70)
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