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Avoid injecting into the thigh on heavy leg training days, as increased local blood flow may alter absorption timing
Smoking and heavy alcohol use can reduce the effectiveness of this medicine, while medications like colchicine or specific antibiotics may alter how your body responds to it
Across GLP-1 trials, about 60% of lost weight returns within the first year and roughly 75% returns over the longer curve, with the fastest regain in the early months. The semaglutide extension follows the same direction. The pattern reflects removal of appetite suppression after major weight loss
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Written protocol with documented endpoints: reconstitution instructions, dose, frequency, expected timeline, and what to monitor