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Patients should contact their prescriber if nausea is severe, persistent beyond the expected adjustment window, prevents adequate oral intake, or if symptoms are accompanied by alarming signs like significant weight loss or dehydration

Use subcutaneous injection, usually in the abdomen or thigh fat

While an increase in metformin exposure was observed, it was not considered clinically relevant by the investigators

Safety of Glucagon-Like Peptide-1 Receptor Agonists: A Real-World Study Based on the US FDA Adverse Event Reporting System Database