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Funding Eli Lilly and Company, Indianapolis, IN, USA, funded this study and paid the Rapid Service Fee

ME/CFS is a common and very debilitating disease for which the origin, or etiology, is unknown

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Nonetheless, early evidence did suggest that mechanisms sensitive to loop diuretics, possibly involving NKCC1 and/or KCCs, may contribute to the phosphorylation of numerous protein substrates in the liver (Lang et al., 1998)

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