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Clinical evidence demonstrates that L-carnitine supplementation reduces fasting blood glucose (37, 39, 53, 54), insulin levels (54, 55), glycated hemoglobin (HbA1c) (56, 57), and ameliorates insulin resistance (37, 53, 54) in NAFLD patients

"The double-digit weight reduction seen after 42 weeks of petrelintide treatment, along with rates of adverse events generally at or below the rates observed with placebo, highlight the potential of this novel amylin agonist as a future first-choice therapy for chronic weight management, said David Kendall, Chief Medical Officer of Zealand Pharma

The treatment typically starts at a low dose, gradually increasing as guided by the physician

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Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients