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The reaction between NO and O forms peroxynitrite (ONOO ), a potent RNS capable of nitrating and damaging cellular structures

Costanzo S, di Niro V, Di Castelnuovo A, Gianfagna F, Donati MB, de Gaetano G, et al

Carnosine dipeptidase II (CNDP2) has been described to support the catabolism not only of cysteinylglycine 57 but also of other dipeptides, such as those containing glutamine 35

Stay sharp

Dose escalation happens every 4 weeks during the titration phase, moving from 2.5 mg up to a therapeutic maintenance dose of 1015 mg

The innovation in this letter is simply highlighting AI as the source of the problem, to make it clear that firms cannot hide regulatory lapses behind automation