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PMC - Assessing the Immunogenicity Risk of Peptide-Related Impurities: Scientific review on immunogenicity risk of peptide impurities

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Zinc is also inhibits the enzyme tyrosine phosphatase 1B (PTP1B), which would otherwise reduce the insulin signal by dephosphorylating the -subunit of the insulin receptor [579]

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Actively studied in Phase 2/3 trials and a major object of incretin literature

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