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The approved GLP-1 class medications as of 2025 include semaglutide (Wegovy for obesity, Ozempic for type 2 diabetes), tirzepatide (Zepbound for obesity, Mounjaro for type 2 diabetes), and oral semaglutide (Rybelsus, now in a higher-dose formulation as Wegovy oral)
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A typical reported timeline: Weeks 1 to 2: Most patients notice modest sleep improvements first
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A 2020 meta-analysis in Obesity Reviews found that patients who implemented structured caloric monitoring before GLP-1 cessation retained 40% more of their weight loss at six months compared to those who began dietary interventions only after stopping [9]