Structurally, Dihexa is derived from angiotensin IV a naturally occurring peptide involved in brain function but has been chemically modified to dramatically enhance its potency and its ability to penetrate the blood-brain barrier
(PubMed) Chaudhary P, Marracci GH, Bourdette DN
However, as demonstrated in our co-expression and pull-down experiments, COP1 does not directly interact with Ube2d3
10.3390/ijms21239330 52 PerovicD.KolencD.BilicV.SomunN.DrmicD.ElabjerE.et al (2019)
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