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Combined effects of electron-beam irradiation and storage time on the chemical and antioxidant parameters of wild Macrolepiota procera dried samples

Glutathione has also emerged a key modulator of xenobiotic toxicity, most notably the persistent organic pollutants which are associated with many diseases of impaired metabolic activity, including diabetes, obesity, and cardiovascular disease

The study results also revealed a significant reduction in malondialdehyde, the livers cell damage marker

274,275 This, in turn, diminishes additional downstream effects, including oxidative stress, the secretion of pro-degradative substances, modifications to cell phenotype (hypertrophy, M1/M2 macrophage phenotype, fibrosis), and damage or deterioration of joint cells (apoptosis, senescence)

Glutathione: Pharmacological Aspects and Implications for Clinical Use in Non-Alcoholic Fatty Liver Disease

System X(c) (-)/GSH/GPX4 axis: an important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy