While compounding during a shortage was a necessary solution, continuing to compound GLP-1s after the shortage has resolvedwithout a true, individualized clinical needis neither legal, ethical, nor in the best interest of patient safety. Dr
[] When symptomatic arsenic poisoning occurs, a symmetrical sensory neuropathy with similarities to the GuillainBarr syndrome may appear even a few hours after ingestion, but is more commonly seen after 28 weeks after exposure
Clinical studies, such as the STEP trials, have shown that adults using semaglutide GLP-1 at the recommended dose (2.4 mg weekly) can lose an average of about 15% of their initial body weight over 68 weeks when combined with healthy lifestyle changes
It is found in the brain
Compounded semaglutide and tirzepatide are not FDA-approved medications
Author contributions MH: Conceptualization, Formal Analysis, Data curation, Writing original draft, Methodology, Visualization, Investigation