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In response to UV radiation, the skin increases melanin production as a protective mechanism

However, while p53 modulates SLC7A11 expression, the expression and activity of SLC7A11 and GPX4 are not associated with SAT1, and only ferrostatin-1 can inhibit ROS-induced ferroptosis in Tet-on cells (Ou et al., 2016)

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It also has significant anti-inflammatory properties and supports gut mucosal integrity