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The Glucuronidation Reaction Smith, Phase II Metabolism, UNC Chapel Hill, 8/2012 17 Clearance mechanisms for the top 200 drugs prescribed in the United States in 2002 Metabolism most important
Furthermore, it has been shown that glycosaminoglycan, such as heparin, heparin sulfate, and dermatan sulfate, can promote HGF-induced c-MET activation through enhancing the binding affinity between HGF and c-MET 16,17,18
These findings have moved the field beyond a simple neuronal replacement model
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