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M6: \(\beta\)=0.77, 95% CI 0.50, 1.03
The article treats this as the main practical trade-off rather than an efficacy question, since it reports no outcome difference between the two schedules
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The short answer: alcohol interacts with GLP-1 medications in ways that can amplify side effects and reduce effectiveness
The circadian rhythm, a roughly 24-hour cycle, governs everything from sleep-wake patterns to hormone release and metabolism
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