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With ongoing research and advancements, retatrutide provides hope for individuals seeking effective management of the comorbidities associated with obesity

104.1 The caregiver experience in amyotrophic lateral sclerosis (ALS): a mixed-methods study to examine the lived experience of caring for people living with ALS and to develop a novel ALS Caregiver Impact Questionnaire (ALS-CIQ) William Nowell 1 , Nadine McGale 2 , Oren Levy 1 , Sarah Wilding 2 , Phoebe Heinrich 2 , Nick Patel 1 , Jinsy Andrews 3 , Diana Rofail 1 1 Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA, 2 Modus Outcomes, Cambridge, Massachusetts, USA, 3 Department of Neurology, Colombia University, New York, USA Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :104.1 Aims This study aimed to develop a conceptualization of the personal experience of caregivers of people living with amyotrophic lateral sclerosis (pALS), and a novel instrument to assess caregiver impact

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As monotherapy: When diet and exercise do not provide adequate glycemic control and when metformin is not suitable due to intolerance or contraindications

This is particularly crucial for those with chronic kidney disease, as they have reduced ability to excrete excess potassium

We cant say for certain if it was the weight loss medications, but theres a high chance that it could be, Kochman said