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It becomes essential only when the dietary intake of methionine and serine is low
These modifications dramatically reduce binding to IGF binding proteins (IGFBP-1 through IGFBP-6), increasing the proportion of bioavailable peptide for receptor interaction in cell-culture systems
These stem from its ability to influence collagen production, improve blood flow to the skin layers, and support elastin
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D., Ramachandran, S., Devamanoharan, P
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