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DOI: 10.1016/j.peptides.2005.01.029 Clinical Development Afamelanotide and EPP Afamelanotide (MT-1), delivered as a subcutaneous slow-release implant, has been studied in multiple randomised controlled trials in patients with erythropoietic protoporphyria (EPP)

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Melanotan II incorporates a cyclic lactam structure and strategic amino acid modifications that enhance resistance to enzymatic degradation relative to linear melanocortin peptides

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