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These cells appear to contribute to the aging process and age-related diseases through the senescence-associated secretory phenotype (SASP), which fosters a pro-inflammatory environment detrimental to tissue function and integrity

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Similarly, Semax , a synthetic peptide with nootropic properties, has been shown to increase brain-derived neurotrophic factor (BDNF) and dopamine function, potentially improving cognitive flexibility and emotional regulation in individuals affected by long-term substance use (Myasoedov et al., 2013)