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This region-specific action is associated with its local stimulation of hormone-sensitive lipase and enhanced fatty acid oxidation, suggesting potential for site-selective metabolic modulation without systemic hormonal changes
in Cell Metabolism , increased NAD availability stimulates PGC-1 through SIRT1 activation, leading to enhanced mitochondrial function and improved metabolic flexibility (Cant et al., Cell Metabolism )
GI-specific protective effects in gastric ulcer, colitis, IBD and NSAID-induced GI injury models where local action is plausible
Minimize dust formation
Suggested Use: Adults take 2 capsules daily, or as recommended by your healthcare practitioner with 8 ounces of water or your favorite beverage
Chemical Structure and Properties Caffeine is a compound with the formula C8H10N4O2
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