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However, it does increase the area under the plasma concentration-time curve (AUC) of metformin by 32%, although this increase is not considered clinically relevant due to metformin's wide therapeutic index

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GLP-1 medications, on the other hand, may not be appropriate for people with a personal or family history of medullary thyroid carcinoma or MEN2, a history of pancreatitis, severe gastrointestinal conditions like gastroparesis, or anyone pregnant or breastfeeding

I decided to go with a 1mg injection on Saturday night, and 1mg injection Tuesday or Wednesday for a total of 2mg weekly

However, some patients do report changes in urination frequency, which is likely due to the bodys adjustment to the medication, hydration, or weight loss

It works by blocking nerve impulses sent to the brain